Can Eden start with any item?

Yes, Eden in The Binding of Isaac can start with a vast range of items, but not any item; they get a random mix of health, stats, an active item, a passive item, and some pickups (keys, bombs, coins) with each run, leading to nearly endless combinations, with some rare exceptions like certain unavailable items, although getting zero items is extremely unlikely.
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What items can Eden not start with?

Notes
  • Key Piece 1, Key Piece 2, Broken Shovel, Broken Shovel and. Mom's Shovel cannot be granted.
  • A new noeden item tag has been introduced, which depicts items that Eden cannot start with. These also include Knife Piece 1, Knife Piece 2, Dogma, Dad's Note, Recall and. Hold.
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Can Eden start with a glowing hourglass?

Item Interactions

Glowing Hourglass: If Eden starts with this item and immediately uses it in the starting room, the room will be reset, and all starting items and trinkets removed.
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Is Eden non-binary?

Character Information

Eden is a non-binary character from The Binding of Isaac.
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How do you spell Eden for a girl?

The name Eden is spelled E-D-E-N, with the pronunciation sounding like "EE-den," referring to the biblical paradise or used as a popular name meaning "delight" or "paradise," derived from Hebrew, and also has Old English roots for "wealth" or "bear cub". 
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The 1 in 1,000,000 Eden Start

What non-binary gender am I?

You might be non-binary if you experience your gender as both masculine and feminine, if you experience your gender as being neither of those things, or if you don't identify with binary, sex-based categories of expectations and societal roles or physical characteristics of your assigned sex.
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What is the hardest boss in The Binding of Isaac?

The hardest boss in The Binding of Isaac is widely considered to be Delirium, due to its chaotic, unpredictable teleporting, rapid transformations, and intense bullet-hell attacks, making it nearly impossible to no-hit; however, Mother and The Beast/Dogma (from Repentance) are also extremely challenging final encounters with unique, difficult mechanics, while The Scourge and early-game bosses like Headless Horseman are noted for their difficulty in specific contexts. 
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What does MissingNo do in TBOi?

MissingNo. is also referenced in the game The Binding of Isaac: Rebirth as "Missing No.", an item that will randomize other items found on each level of the game as well as their attributes while held.
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Can the lost take devil deals?

Yes, The Lost in The Binding of Isaac can take Devil Deals for free, which is a huge advantage, but they can only select one item per room; taking one item causes all other deals in that room to disappear, making them powerful for getting strong items early without health cost. This is a core strategy, often preferred over Angel Deals because The Lost's free health (via Holy Mantle) makes the risk/reward of Devil Deals very favorable.
 
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Is there a downside to using Glowing Hourglass?

This means that if Glowing Hourglass is used twice in succession, they will rewind as normal with the first use to the previous room, then, upon second use, everything will be rewound, but the player will not be teleported to the room previous to the one they just teleported to and will instead find themselves ...
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How to unlock the D6 as a starting item for Isaac?

To unlock the D6 for Isaac in The Binding of Isaac, you must first unlock the character Blue Baby (???) by defeating Mom's Heart 10 times, then play as Blue Baby and beat the final boss of the Cathedral, which is Isaac himself, after which Isaac will start with the D6. 
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Can I name my son Eden?

Gender: The name Eden is more often used as a girl's name but it is gaining popularity for boys too.
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What is the 0 Pokémon?

Pokémon #0 refers to Victini, a Mythical Pokémon given a special designation in the Unova Pokédex (Generation V) to signify its unique status, representing "zeroth" first place and the beginning of a new era, while also being associated with the Roman numeral 'V' for Generation 5 and its power to bring victory. It's a symbolic number, as official National Pokédex numbers start from #001 (Bulbasaur).
 
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Does catching MissingNo ruin your game?

Catching Missingno. in the original Pokémon Red and Blue doesn't usually "ruin" your game permanently but causes significant glitches, primarily duplicating items in your sixth bag slot and scrambling some graphics, but it can permanently corrupt your Hall of Fame data. While often harmless otherwise and even useful for item duplication, there's a small risk of more severe data corruption, so it's generally advised to avoid it if you're worried about your save file.
 
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What does R do in TBOi?

R Key can be used on The Chest or Dark Room to completely restart a run and get even more items.
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What is 1001% Isaac?

It unlocks when you have around 276 secrets, that was the total o secrets of Afterbirth, every DLC has its own 100% complete achievement, it's not bugged, you have the number of secrets to unlock the achievement, everything is fine.
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Am I straight if I'm non-binary?

We Have a Variety of Sexual Orientations

Similarly, sexual orientation and gender identity are two separate things. Someone can be cisgender and queer, and they can also be transgender or nonbinary and straight. Or, they can have any of these gender identities and choose not to label their sexual orientation.
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Is there a "right" way to express my gender?

Your transition and gender expression is completely up to you and what feels comfortable and safe. Whether you consider all, none, or a few new ways of transitioning to express your gender – you are the gender you feel you are.
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Is it normal for a 12 year old to be non-binary?

You may worry that your child's exploration of different gender preferences and behaviours is not "normal". However, this is not the case. A young child's exploration of different gender identities is quite common. However, for some children this may continue into later childhood and adolescence.
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