Can you still go to the Soul Cairn as a Dawnguard?

Yes, as a Dawnguard member, you must go to the Soul Cairn to progress the main quest, and you can enter either by having Serana partially soul-trap you (temporary penalty) or by becoming a Vampire Lord, though the latter requires a cure to continue the Dawnguard questline. The soul-trap method lets you keep your stats normal by finding your soul gem, making it the preferred path for most Dawnguard players.
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Why can't I enter the Soul Cairn again?

You cannot enter the soul cairn unless you are vampire or soul trapped by Serana. She cannot soul trap you again once the dialogue option has been passed. You have one chance to enter the souls cairn this way.
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Should I become a vampire or let Serana Soul trap me?

For most players, letting Serana soul trap you (partial soul trap) is the better choice, as it's a minor debuff in the Soul Cairn you can recover from, while becoming a Vampire Lord locks you into vampirism (unless cured), potentially hindering the Dawnguard questline and causing issues if you want to remain mortal or a Werewolf; you can always become a Vampire Lord later if you want, even after the main quest. 
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Can you go back to the Soul Cairn in Skyrim?

Yes, you can go back to the Soul Cairn in Skyrim after the main quest, but you need to be a vampire or partially soul-trapped to re-enter through the main portal at Castle Volkihar. The easiest way to get there is by fast-traveling to the Castle Volkihar Balcony, which takes you right to the portal room. 
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Can you side with the Dawnguard and still become a Vampire Lord?

Yes, you absolutely can become a Vampire Lord after finishing the main Dawnguard questline in Skyrim by asking Serana to bite you, even if you sided with the Dawnguard. This ability remains available even after the DLC concludes, allowing you to switch between forms, though being a vampire will make the Dawnguard hostile and stop most of their radiant quests unless you cure yourself. 
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Skyrim: Dawnguard - How to get your SOUL ESSENCE back in the Soul Cairn! *spoilers*

How many times will Serana make you a vampire?

Serana can turn you into a Vampire Lord an unlimited number of times, provided you've completed the Dawnguard questline and haven't persuaded her to cure herself. After the main quest, you can simply ask her to transform you as often as you like, but you'll need to get cured by Harkon or a priest to interact normally with the Dawnguard again. 
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Can I become a werewolf again after Dawnguard?

With Dawnguard, Aela only gives you the chance to be a werewolf again once after curing yourself.
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Why won't it let me in the Soul Cairn?

If access to the Soul Cairn is gained by becoming a Vampire Lord, and the condition is cured immediately after leaving, reentering will not be possible. Get Serana to turn the Dragonborn back into a Vampire Lord before returning to Valerica's Study for the first time and it should be possible to enter the Cairn.
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How many times can you enter the Soul Cairn?

From UESP: "the Soul Cairn may be re-entered at any time. However, if you enter as a vampire and are subsequently cured of vampirism, you'll need to become a vampire again in order to re-enter. "
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Is the Soul Cairn a plane of Oblivion?

Yes, the Soul Cairn is a plane of Oblivion, but it's unique because it's not ruled by a Daedric Prince but by the Ideal Masters, powerful, disembodied spirits of ancient necromancers who created it to trap and trade souls, making it a desolate realm of undeath and tormented spirits, according to The Elder Scrolls lore.
 
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What happens if Serana cures herself?

If you cure Serana in Skyrim's Dawnguard DLC, she becomes mortal, loses her Vampire Lord powers and bloodcursed arrows, and her eyes change, but she retains much of her personality, complaining about the sun and still disliking temples, making it a choice for roleplaying rather than major gameplay benefit, though she can then be healed by normal Restoration spells.
 
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Will the Dawnguard hate me if I become a vampire?

Before you join, showing up as a vamp (no matter the stage) will make them hostile. If you've already joined, they aren't going to attack you, but you'll be unable to continue their quest or doing any jobs for them.
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Will Serana still follower if you choose Dawnguard?

Yes, you absolutely can get Serana as a follower if you join the Dawnguard; she's a core companion for the entire Dawnguard DLC questline, regardless of which faction (Dawnguard or Vampires) you ultimately side with, and remains a permanent follower after completion if you choose. She'll follow you through most of the main story as an essential guide, and after the questline, she'll stay at Fort Dawnguard (or Castle Volkihar if you chose vampires) and can be recruited indefinitely. 
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Is it better to become a vampire or get soul trapped?

You should become partially soul trapped, as it makes little difference, and you can always re-enter the Soul Cairn and regain it from a chest; Valacia will even tell you where it is. Become a vampire and you can go in as one fine, but you'll miss out on other side-quests.
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How to unbecome a vampire in Skyrim?

To not be a vampire in Skyrim, cure early-stage vampirism (within 3 days) with a Potion of Cure Disease, a shrine blessing, or Vigilant of Stendarr, but for full vampirism, find Falion in Morthal to perform a ritual with a filled Black Soul Gem, or join the Companions to become a werewolf, which removes vampirism. 
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Can the keepers in the Soul Cairn respawn?

Boneyard Keepers are towering servants of the Ideal Masters who reside in the Soul Cairn. Charged with the incarceration of Valerica, they herd imprisoned souls and drain their energy to maintain the barrier in front of the Boneyard. Three appear during Beyond Death and do not respawn.
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Is it better to join Dawnguard or Vampires?

Choosing between Dawnguard or Vampire in Skyrim's DLC depends on your playstyle: Dawnguard offers powerful crossbows, unique sun-based spells, trolls, and a focus on traditional vampire hunting, while Vampires provide the potent Vampire Lord form with unique powers, vampire-specific jewelry, and a darker roleplaying experience, though becoming a vampire early can alienate Dawnguard members and vendors. You can even join the Vampires later as a Dawnguard member for a mix of rewards, but expect bugs with Dawnguard interactions.
 
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How many times will Aela turn you into a Werewolf?

In Dawnguard, Aela is able to give lycanthropy again, if the Dragonborn decides to cure it in favor of vampirism. Points expended toward the Werewolf skill tree cannot be undone or moved to other skill trees, which includes the Vampire Lord skill tree. She will only do this once, however.
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Can I become a Vampire Lord again?

Just ask Serana to turn you. Her and Aela will turn you into a Vampire Lord or Werewolf respectively as many times as you want/need, and their non-human forms will overwrite each other if I recall correctly.
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Can I enter the Soul Cairn again?

Yes, you can go back to the Soul Cairn in Skyrim's Dawnguard DLC, usually by re-entering through the portal at Castle Volkihar after finishing the main quest or by becoming a vampire, but you'll need to be a vampire or have been partially soul-trapped to re-enter via the portal, though some methods (like console commands on PC or specific quest steps) allow for mortal entry too, notes Reddit users and Steam Community users. 
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How do you fix the Arcwind point glitch?

The Arcwind Point glitch in Skyrim, where the quest doesn't complete after learning the word, is often fixed by visiting and learning the word at Northwind Summit, as this triggers the completion for the associated Drain Vitality shout. On PC, you can also use console commands like SetStage FreeFormHighHrothgarA 20 or SetLocationCleared 000fd685 1, or install the Unofficial Skyrim Special Edition Patch (USSEP). 
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Why won't Serana follow me anymore?

Serana stops following you due to bugs, usually after being told to "wait" during the Dawnguard questline (especially between "Beyond Death" and "Touching the Sky"), getting stuck in the environment, or conflicts with other mods; fixes involve completing the current quest, waiting several days in-game, fast-traveling, using console commands (PC), or reloading an earlier save, with the Unofficial Patch helping prevent issues.
 
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Why won't Aela turn me into a werewolf?

Aela will only restore your lycanthropy once. So if you get cured, she can make you a werewolf again.
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Is it better to be a Vampire Lord or werewolf in Skyrim?

In Skyrim, the choice between Vampire Lord and Werewolf depends on playstyle: Vampire Lord offers versatile magic/melee with powerful drain/choke spells, great for mages, but suffers severe sunlight weakness in Survival Mode; Werewolf is a pure melee powerhouse with high damage and fast travel, ideal for warriors, but lacks ranged options and the transformation is temporary. Werewolves get passive boosts and can't be cured easily, while Vampires get Illusion/Stealth buffs and can switch forms often, making them better for diverse builds but vulnerable to fire and sun. 
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Can you still become a Vampire Lord if you refuse Harkon?

Yes, you absolutely can become a Vampire Lord even after refusing Harkon's offer; you just need to get turned by Serana later in the questline or after completing it, either during "Chasing Echoes," "Kindred Judgement," or as a follower, as long as she hasn't been cured of her vampirism. This allows you to get the Vampire Lord form and powers without siding with Harkon initially, though it might affect your relationship with the Dawnguard if you're actively helping them. 
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