Do enemies drop Madman's knowledge?

Yes, some enemies in Bloodborne do drop Madman's Knowledge, though often with very low drop rates, including the Children of Rom (spiders), Celestial Larvae, and specific Yahar'gul Hunters, but it's also found abundantly as fixed items in the world and dungeons. Farming these enemies for drops is generally not efficient; it's better to find the scattered items or farm Chalice Dungeons.
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Do any enemies drop Madmans knowledge?

There are Madman's Knowledge treasures in all parts of the game (Main Story, the Old Hunters DLC, Preset & Root Dungeons), as well as item drops from enemies (Main Story, the Old Hunters DLC, Preset & Root Dungeons).
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What makes you lose insight in Bloodborne?

Three ways you lose insight: (1) Getting trapped in the grab attack of Brainsuckers. (2) Spending it at the insight store. (3) Using the Small Resonant Bell to summon cooperators.
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Where to get Madman's knowledge in Bloodborne?

In Bloodborne, Madman's Knowledge is found scattered across Yharnam in numerous corpse locations, especially abundant in Cathedral Ward, Central Yharnam, Old Yharnam, and Forbidden Woods, acting as consumable items to gain Insight (the in-game "eye" stat). You can find them on bodies in sewers, behind enemies, on rafters (near Eileen), as quest rewards (from Adella), or sometimes replacing other loot in chests within Chalice Dungeons.
 
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Is there a downside to Insight Bloodborne?

Insight is bad but not terrible. It will decrease your frenzy resistance which is a bad thing as it decreases your defense vs winter lanterns, cross-carrying mobs on Cathedral Ward or bloodletter PvP, and it also decreases bestiality which is a stat used to improves your beast claws and beast blood pellets.
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Bloodborne™ | Location of the first "Madman's Knowledge"

Does having 99 Insight do anything?

The maximum Insight attainable is 99. Afterwards, any occurrence or action that would normally increase Insight will do nothing. Consuming a Madman's Knowledge, Great One's Wisdom, Blood Dreg, or a One Third of Umbilical Cord simply uses the item but provides no benefit.
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Is 40 or 50 vitality better Bloodborne?

Practically speaking, a player should try to have between 40 and 50 Vitality to squeeze as much health value from the stat as possible. Along with Endurance, this is tied as the most important stat to level up.
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Is there a way to farm insight?

You can essentially cap out your insight by spamming chalice dungeons. Every time you see/defeat a boss, it'll give you a few. It's time consuming, but that'd be the only reliable way to farm. Also can farm knowledge of madman from celestial children.
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How many insight does it take to see the amygdala?

In the game Bloodborne, you need 40 Insight to see the Lesser Amygdala creatures hanging from buildings in areas like Cathedral Ward before the Blood Moon event; otherwise, they become visible after defeating Rom and triggering the Blood Moon phase, Fextralife forum, GameFAQs forum, Bloodborne Wiki - Fextralife. Higher Insight also reveals other hidden details, like new enemy attacks and changes in the Hunter's Dream, but decreases Frenzy resistance, Bloodborne Wiki - Fextralife. 
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Should I sell my Madman's knowledge?

Don't sell them. You can buy stuff with Insight so just keep them in your inventory and use them when you feel the need. Also, Insight does not affect the difficulty of enemies.
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Does Bloodborne have NSFW?

Sex & Nudity

Statues of women without clothing are shown at Cainhurst Castle. No genitalia appear to be shown, nipples are shown on a couple. Some monsters appear nude and their rears exposed.
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Why is high insight bad in Bloodborne?

It also changes the movesets of enemies and the more you have of it the harder the game gets. Insight allows you to see things with your EYES YOUR EYES YES YOUR EYES. Grant us eyes as you once did for the vacuous ROM. There's basically no advantages in having a high insight besides (apparently) some lore/visual stuff.
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How to get insight fast in Bloodborne?

The fastest way to get Insight in Bloodborne is by repeatedly completing easy Chalice Dungeons (like Depth 1) via Quick Match or specific glyphs (e.g., 3N7Q for easy bosses), farming bosses for 2 Insight each, and collecting Madman's Knowledge/Great One's Wisdom from chests in those dungeons, especially if you're helping others with the Small Resonant Bell, as bosses give insight and you get insight for helping. 
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What is the rarest enemy in Bloodborne?

The Labyrinth Mole is a rare enemy in Chalice Dungeons that resembles a star-nosed mole.
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Why is everyone turning into beasts in Bloodborne?

Through the Healing Church's medical advances using the Old Blood, Yharnam grew into a powerful city. Unfortunately, as Willem predicted, the imbibed began to turn into the beasts over time.
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Which enemies can you parry in Bloodborne?

Examples of bosses that can be parried are Father Gascoine, Martyr Legarious. Blood-Starved Beast, and some others. Lmax gave you some good tips, but don't parry after their attack. As they are raising their arm to swing at you is the time to parry.
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Are all great ones female Bloodborne?

He is also the only Great One explicitly referred to as male, with all the others' genders either female or undefined (assuming the Great Ones even have humanly-definable genders).
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What is the invisible monster that grabs you in Bloodborne?

In the Cathedral Ward, an Amygdala can grab and crush the player, immediately triggering a Frenzy status effect.
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What weapon is good against the Amygdala?

The church pick works especially good against amygdala overall. Besides that stick close to the small arm on the side and take swings at it.
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Is Bloodborne harder with more Insight?

No, insight doesn't change the difficulty of the bosses. They probably had zero insights because Beast Blood Pellets are more effective with low insight. Thank you! Insight makes changes to the world so yes but not necessarily harder.
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What's the max Insight in Bloodborne?

In Bloodborne, the maximum Insight a player can have is 99, representing ultimate cosmic knowledge, but reaching this cap makes the game significantly harder by increasing Frenzy buildup and enemy difficulty (like new enemy spawns and tougher movesets), with the only tangible benefits being access to specific items and seeing previously invisible cosmic entities like Amygdala; after 99, consuming more Insight items does nothing, notes www.fandom.com. 
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Can I lose Insight in Bloodborne?

Yes, you can lose Insight in Bloodborne by spending it on items at the Messengers, having it forcibly drained by Brainsucker enemies (who suck it from your brain), or by using online co-op bells (which costs 1 Insight per use). You don't lose it by dying, but gaining Insight makes the world harder by spawning new enemies and attacks. 
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Is ng+ hard in Bloodborne?

Ng+ has a higher difficulty with enemies with more damage and mkre health. But you stay the same level that you ended your previous game with.
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When to stop leveling in Bloodborne?

The level cap in Bloodborne is effectively 544, but each stat has soft caps at 25 or 30 and again at 50. Most players stop leveling around 100-120 because returns diminish sharply beyond those points and the game is balanced for that range.
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