Does shot speed affect mom's knife?

Yes, in The Binding of Isaac, Shot Speed does affect Mom's Knife, increasing how fast the thrown knife travels across the screen, alongside other stats like Range (distance) and Tears (faster charge/attack rate), though some players debate its precise impact compared to Tear rate.
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Does mom's knife override technology?

Technology - Mom's Knife overrides Technology with no special effect. Technology 2 - Mom's Knife overrides Technology 2, with the 65% damage still applying to Mom's Knife, making this synergy not recommended. Although the Technology 2 laser will still appear to fire, it is purely cosmetic and deals no damage.
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Why is Mom's knife so good?

Mom's Knife is a powerful weapon that replaces the player's tears with a large knife. This item completely alters the player's attack style, allowing them to throw and control the knife with precision. The thrown knife deals high damage and pierces through enemies, making it an incredibly potent weapon.
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Does mom's knife scale with damage?

Damage dealt by the knife depends on its charge state. The knife deals 2× Isaac's damage when held and 6× damage at about 1/3 of full charge. The knife damage quickly drops to 2× Isaac's damage when returning regardless of charge state. Further charging only increases its maximum range.
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Does mom's knife override ipecac?

Mom's Knife: Knife turns green, may poison enemies, and removes Ipecac's damage increase. Also adds +4 flat damage bonus. Also adds +2 flat damage bonus. The thrown knife can explode once on enemy contact while being sent out, but not while returning.
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How fast can you unlock Mom's Knife?

Does 20/20 work with mom's knife?

Mom's Knife: Overrides 20/20. Monstro's Lung: Overrides 20/20. Mutant Spider: Overrides 20/20. Sad Bombs: Does not affect the number of tears when bombs explode.
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Can moms knife open the door?

Mom's knife is now able to open the door leading to the Corpse, like it used to in Antibirth. In addition to Mom's Knife, the Forgotten's Bone Scythe and Tainted Eve's Sumptorium are also able to open the door.
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Does chocolate milk work with mom's knife?

Chocolate Milk + Mom's Knife? How do these two items interact with each other? They don't. Mom's Knife completely overrides Choc.
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Does mom's knife work with blindfold?

No, Mom's Knife does not work with the Blindfolded effect in The Binding of Isaac, as the condition prevents all tear-replacing attacks like Mom's Knife, Brimstone, and Ludovico Technique, effectively making it unusable and invisible. This is because Blindfolded challenges are designed to limit shooting, and Mom's Knife is treated as a tear replacement, even though it's a unique attack. 
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Can Lilith use mom's knife?

Mom's Knife: Gives Incubus a smaller version of the item with the same base range as Isaac; However, Lilith will not get this to use due to her blindfold. This knife can be used with Incubus to give it contact damage with no danger to Lilith.
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What makes mom so special?

The Mother is the most prominent figure in your life who keeps giving without expecting anything in return. Her love is selfless, which you can never ever receive from anyone else in your entire life. She loves you even when you are unhappy with yourself and it is her affection that makes you a better person.
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What knife does Ellie have?

Ellie uses a specific Italian stiletto switchblade, a classic automatic folding knife with a bayonet-style blade, often featuring wood or ivory-like handles, given to her by her mother, Anna. It's her signature weapon for quick, close-quarters stabs and ambushes, prized for its small size and fast deployment in the harsh world of The Last of Us.
 
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Does mom's knife work with a Dr. Fetus?

Mom's Knife: Overrides Dr. Fetus. My Reflection: The bombs lose momentum and slide back towards Isaac, making self-damage very likely.
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Does rubber cement work with mom's knife?

Mom's Knife: Overrides Rubber Cement. Knights that are normally invulnerable from the front. Sinus Infection: Boogers stick to enemies, but otherwise they bounce normally. Spectral tears: Overridden by Rubber Cement.
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Does bird's eye work with mom's knife?

Mom's Knife: Overrides Bird's Eye.
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Does Neptunus work with mom's knife?

Mom's Knife: depending on Neptunus charge, 0 to 3 water (pseudo-)knives are launched for each knife. Spirit Sword: sword's swing attack is transformed into single spin attack, if you have enough Neptunus charge.
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Does haemolacria work with mom's knife?

Mom's Knife: Haemolacria tears fire while Mom's Knife is charging. Overridden by Mom's Knife. Stats change still apply; however, the tears down is instead a +10 Tear Delay.
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How does mom's knife work with the forgotten?

Mom's Knife: The knife will attach to The Forgotten's bone club, forming a scythe. Increases the size of both the melee swing and the bone throw and allows a single melee swing to deal damage to an enemy twice instead of just once and bone toss attack to deal damage multiple times.
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Does Swiss Miss work with milk?

Yes, you absolutely can make Swiss Miss with milk for a richer, creamier hot chocolate, and it's often recommended over just water for better flavor, though you might want to use hot milk or dissolve the powder in a little hot water first to prevent clumps. The packets already contain nonfat milk, so using fresh milk makes it even more decadent, and you can adjust ratios to taste, even mixing in some water or half-and-half. 
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Is soy milk polyphemus worth it?

Taking Soy Milk with Mutant Spider, Polyphemus, Eve's Mascara, or Inner Eye is still not recommended, as the DPS up from Soy Milk with these items is still quite low (and in some cases, it becomes DPS neutral) and will still scale very poorly with any tears up.
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Is soy milk worth it Isaac?

At base damage, Soy Milk is a very small DPS up. With a tear delay of 8 or lower, Soy Milk becomes a DPS down. The more tears per second before obtaining Soy Milk, the greater the decrease in DPS. Soy Milk's damage down stat also significantly decreases tear size.
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What do you unlock after beating mom's heart 11 times?

Unlock Method

After being killed 11 times, Mom's Heart is permanently replaced by It Lives. However, even after being replaced by It Lives, there are a few circumstances in which Mom's Heart can still be fought: It can still appear in the Nightmare Boss wave of Chapter 4 in Greed/Greedier Mode.
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How to get mom's knife piece 2?

Knife Piece 2 is located in Mines II. Somewhere on the floor, there will be a room containing four buttons. Next to each button is 1 to 4 small pebbles, indicating the order in which to press them. After pressing the four buttons, Knife Piece 2 will appear in the center of the room.
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