Is it possible to avoid tuberculosis in RDR2?

No, you cannot avoid tuberculosis (TB) in Red Dead Redemption 2 (RDR2); it's a central, unavoidable plot point for Arthur Morgan, contracted from Thomas Downes, leading to his eventual death, though how you play affects his final days and honor. While some might try to halt progress, Arthur's TB is terminal and part of the story's scripted events, with no in-game cure or way to prevent infection after the initial encounter, as IMDb notes.
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Can you avoid getting tuberculosis in Red Dead Redemption 2?

No, you cannot avoid getting tuberculosis in Red Dead Redemption 2 as it's a core, unavoidable storyline event that happens during a mandatory mission in Chapter 2 with Thomas Downes, driving Arthur Morgan's character arc and the game's plot, though some players experiment with delaying the mission or even killing Downes early, it only postpones the inevitable or halts game progress, as it's central to the narrative.
 
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Is there a way to not do the Thomas Downes mission?

You can't permanently avoid Thomas Downes in Red Dead Redemption 2 as his mission is crucial for story progression and Arthur getting tuberculosis, but you can delay or "cancel" the mission temporarily by deliberately failing it in specific ways (like riding away) to allow for other activities before the story forces you to confront it, notes Reddit users and Reddit users. The game integrates his infection into the narrative, making it unavoidable to progress, so players often find exploits to postpone it for free-roam enjoyment in Chapter 2, say Reddit users https://www.reddit.com/r/RDR2 and Reddit users https://www.reddit.com/r/RDR2. 
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Is there any way to get rid of Arthur's tuberculosis?

The doctor who visits Arthur explicitly mentions that the disease is not curable. Tuberculosis makes Arthur slower, less likely to heal himself with food and drink. A special item in the game, the 'Owl Feather Trinket', powers-up Arthur and partially alleviates the symptoms, but it does not cure tuberculosis.
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How did Arthur not give everyone TB?

In Red Dead Redemption 2, Arthur Morgan didn't spread TB to the whole gang because, while contagious, it requires significant exposure, and he often tried to distance himself after realizing he was sick, plus TB can be in a latent (inactive) phase, meaning he wasn't always actively contagious, and game mechanics prioritize story over strict infection realism. He contracted it from Thomas Downes coughing blood in his face, but his attempts to minimize close contact and the gang's varied activities meant fewer opportunities for transmission, especially to someone like Micah, notes this YouTube video and this Quora post. 
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Secret method to cancel the TB mission in Red Dead Redemption 2

What if Micah got TB instead of Arthur?

If Micah Bell got tuberculosis (TB) instead of Arthur Morgan in Red Dead Redemption 2, it would drastically alter the story: Micah, the insidious rat, would become physically weak, potentially dying early, preventing his ultimate betrayal and allowing Arthur to live longer, find redemption, and perhaps secure a better future for John Marston's family, making the ending far more poignant and less tragic, with a strong sense of poetic justice as Micah succumbs to the "black lung" he mocked Arthur for. 
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What triggers Arthur's TB?

Arthur Morgan got tuberculosis (TB) in Red Dead Redemption 2 after being coughed on by Thomas Downes during an early mission where he forcefully collected a debt, contracting the airborne bacteria, which leads to his eventual terminal illness and death later in the game.
 
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How long until Arthur gets tuberculosis?

Obviously, it is difficult to work out how long it takes for Arthur's case of TB to incubate, however a rough estimate is around 3 months. This matches fairly well with the game's story, based on certain events and missions occurring.
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Can you play as Arthur after you finish RDR2?

No, you cannot officially play as Arthur after finishing the main story and epilogue, as he is deceased; the game transitions to John Marston, but you can use a specific glitch in the epilogue to temporarily play as Arthur by replaying an early mission, allowing for free-roam and side content as him, though it's unofficial and might have limitations. 
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Which is the hardest mission in RDR2?

The hardest mission in RDR2 is often debated, but "American Venom" is a top contender due to its intense, cover-less shootout with endless enemies and Micah, while other difficult missions include the challenging stealth/action of "Blood Feuds, Ancient and Modern", the frustrating "The Sheep and the Goats", and optional challenges like catching the White Arabian.
 
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What happens if you shoot one of the twins in RDR2?

If you shoot one of the twins during the RDR2 "Oh, Brother" stranger mission (Proetus or Acrisius), the mission immediately fails, resulting in a "Mission Failed" screen, as they are performing a dangerous stunt for Helen, not a fight to the death, and your action interrupts their performance, causing the other brother and Helen to react in horror and shock before the game ends the encounter. 
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Does Mrs. Downes forgive Arthur?

Yes, Edith Downes ultimately accepts Arthur's money and offers a form of forgiveness or, at least, closure, telling him to use his final days for good, though she makes it clear she still resents him and his actions ruined her family, but Arthur's genuine remorse and help allow her to move on with her son. While she initially refuses and expresses deep hatred for Arthur's part in her husband's death and her subsequent plight, she relents when he insists, accepting the money to start a new life, and he leaves feeling he's done some good.
 
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Does Arthur get tuberculosis in every ending?

Arthur's diagnosis isn't drawn out, nor does it happen at the end.
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Is it possible for Arthur to not get sick?

You cannot stop Arthur Morgan from getting sick with tuberculosis in Red Dead Redemption 2; it's a core part of the story that happens during the "Money Lending and Other Sins III" mission with Thomas Downes, and there's no way to prevent it or cure it, though some items and side missions can alleviate symptoms or slightly affect the ending. Players have tried wearing masks or skipping missions, but the infection is unavoidable for the main narrative.
 
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Who gave Arthur Morgan tuberculosis?

Arthur Morgan got tuberculosis (TB) from Thomas Downes, a debtor he was roughing up for Leopold Strauss in Chapter 2; during the confrontation, the sick Downes coughed blood and spat in Arthur's face, transmitting the disease, a pivotal moment marking the start of Arthur's terminal illness.
 
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Can you find Arthur's body as John?

Yes, as John Marston in the epilogue of Red Dead Redemption 2, you can find Arthur Morgan's grave on a mountain near the Mysterious Hill Home (east of Donner Falls/Baka Station) after completing the story, and visiting it triggers a special cutscene with unique journal entries and animations depending on Arthur's honor level.
 
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Can you go back to Blackwater as Arthur?

No, you cannot freely explore Blackwater as {!nav}Arthur Morgan in Red Dead Redemption 2 because the game locks you out with constant Pinkerton attacks and invisible snipers, making it impossible to enter the town or New Austin without being killed, unless you use specific story missions or glitches to bypass the barriers temporarily. The only legitimate story entry is a stealth section in Chapter 3 ("The First Shall Be Last"), but otherwise, it's a "Wanted Dead or Alive" zone. 
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Does the epilogue affect the main story?

They can portray an event that occurs possibly weeks, months, or years ahead of the reality in which your main plot has effectively concluded. They move the story along, allowing for changes in the lives of your characters, and while tangential in some cases, epilogues have an impact on everything that has come before.
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Could Arthur's TB be cured?

No, you cannot cure Arthur Morgan's tuberculosis in Red Dead Redemption 2 because it's a terminal, central plot point, reflecting historical realities where TB (consumption) was incurable, though certain in-game items like the Owl Feather Trinket can lessen symptoms, the disease always progresses, leading to his eventual death.
 
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Does Arthur tell Dutch he has tuberculosis?

Micah constantly calling him 'black lung' should have clued him in, but no Arthur never explicitly told Dutch he had TB.
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What mission triggers Arthur's tuberculosis?

Arthur Morgan gets tuberculosis (TB) in Red Dead Redemption 2 during the mission "Money Lending and Other Sins III" in Chapter 2, when he violently beats the indebted Thomas Downes, who coughs blood directly into Arthur's face, infecting him. The disease, also known as consumption, takes time to show symptoms, appearing prominently later in Chapter 5 and being officially diagnosed in Chapter 6, driving much of Arthur's character arc and quest for redemption, notes Red Dead Wiki and YouTube video. 
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Why is Arthur called Black Lung?

Arthur Morgan is called "Black Lung" in Red Dead Redemption 2 because of his worsening tuberculosis, which causes a persistent cough, making him sound like a coal miner with Coal Workers' Pneumoconiosis (Black Lung Disease), a disease known for lung damage and coughing up black mucus; the name is an insult from Micah Bell, who mocks Arthur's declining health and weakness.
 
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How did Morgan get TB?

Arthur Morgan got tuberculosis (TB) in Red Dead Redemption 2 from a debtor, Thomas Downes, who coughed blood into his mouth during an early mission in Chapter 2, infecting him with the bacteria, although the illness doesn't manifest fully until later in the game, leading to his tragic fate.
 
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Why does Arthur keep coughing in RDR2?

Arthur Morgan coughs in RDR2 because he contracts tuberculosis (TB) from Thomas Downes, a debtor who coughs blood into his face during an unavoidable mission in Chapter 2; this illness progressively worsens, causing severe coughing fits, health decline, and eventual death, highlighting the game's themes of mortality and inevitable decline.
 
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