Is Kuru 100% fatal?

Kuru is a rare, incurable, and almost 100% fatal prion neurodegenerative disease that caused an epidemic among the Fore people in Papua New Guinea due to ritualistic cannibalism. It results in severe tremors, loss of coordination, and death within 6 to 12 months after symptoms start.
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What virus is 100 fatal?

Rabies virus has a characteristic bullet-shaped virion structure. Rabies virus infection in mammals is nearly 100% fatal if left untreated.
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Do prions have a 100% death rate?

Key points. Prion diseases occur when proteins in the body misfold and cause brain damage and other symptoms. Prion diseases are rare; some affect people, and some affect animals. Prion diseases always lead to death within months to years after symptoms begin.
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Has anyone ever survived kuru?

Recently, researchers discovered that some of the people who survived the kuru epidemic carry a genetic mutation called V127, whereas those who developed kuru did not have this mutation.
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Is kuru always fatal?

Yes, kuru is universally and invariably fatal; there is no cure, and death typically occurs within a year (often 3 to 23 months) of symptoms appearing, due to progressive neurological degeneration, malnutrition, or secondary infections like pneumonia. This rare prion disease, historically spread through ritualistic cannibalism in Papua New Guinea, causes severe tremors, loss of coordination, and eventually renders victims unable to sit, stand, or swallow.
 
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Did sexist gaslighting help spread a 100% FATAL laughing condition that ANYONE can get? (*YT MA*)

Did early humans cannibalize?

Yes, archaeological evidence strongly suggests that early humans practiced cannibalism, with findings from millions of years ago showing butchery marks on human bones, indicating it wasn't just a survival tactic but also potentially for ritualistic, cultural, or social reasons, not solely nutritional needs, and was fairly common across prehistoric times. 
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What plague has a 100% death rate?

Pneumonic plague is the most severe manifestation of plague, with mortality rates approaching 100% in the absence of treatment. Its rapid disease progression, lethality, and ability to be transmitted via aerosol have compounded fears of the intentional release of Y. pestis as a biological weapon.
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What is the #1 killer disease?

Globally and in the U.S., Heart Disease (Cardiovascular Disease) consistently remains the leading cause of death, followed by Cancer and then Accidents (Unintentional Injuries), though specific rankings and figures shift slightly by year and location. Cardiovascular diseases, including heart attacks and strokes, kill more people in the U.S. than cancer and accidental deaths combined. 
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What diseases have a 0% survival rate?

Includes Creutzfeldt–Jakob disease and all its variants, fatal insomnia, kuru, Gerstmann–Sträussler–Scheinker syndrome, Variably protease-sensitive prionopathy and others. No cases of survival, invariably fatal.
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Which type of plague had a 50% survival rate?

Without treatment, plague is nearly always fatal. With treatment, there's a 5 to 15% mortality (death) rate for bubonic plague and around a 50% mortality rate for pneumonic and septicemic plague.
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What illnesses have no cure?

Incurable diseases are chronic, progressive, or genetic conditions like Alzheimer's, Parkinson's, ALS, advanced cancers, MS, HIV/AIDS, and severe heart/kidney disease, which currently lack definitive cures, though treatments manage symptoms and improve quality of life, shifting focus to palliative or life-limiting care to maximize well-being despite the illness's persistence. Research into genetic targets, RNA therapies, and new drugs aims to change this, but for now, many conditions remain untreatable long-term, requiring personalized symptom management.
 
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Which plague killed 75% of the population?

Plague has most famously been called "the Black Death" because it can cause skin sores that form black scabs. A plague epidemic in the 14th century killed more than one-third of the population of Europe within a few years. In some cities, up to 75% of the population died within days, with fever and swollen skin sores.
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What is the deadliest virus on Earth?

Using the “case fatality rate” metric to determine what virus is the deadliest, rabies would likely come out on top. That's because, if an infection becomes symptomatic, rabies is fatal to humans in more than 99 percent of cases. Globally, approximately 59,000 people die from rabies every year.
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What diseases are close to a cure?

We're getting closer to cures/elimination for diseases like HIV, viral hepatitis, and STIs, with global goals set for 2030, plus major advances in cancer treatments (especially CAR T-cell therapy for blood cancers and targeted drugs for specific cancers like ALK-positive lung cancer), and potential for earlier Alzheimer's/neurodegenerative disease detection/prevention, while diseases like malaria and yaws see renewed eradication efforts. 
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What illness is a silent killer?

A "silent killer" disease is a serious health condition, most commonly Hypertension (high blood pressure), that causes significant damage over time without obvious symptoms, making it hard to detect until severe complications like heart attack, stroke, or kidney failure occur. Other conditions like diabetes, certain cancers, and high cholesterol also act as silent killers by progressing undetected, damaging organs, and increasing mortality risk, with regular monitoring being the only way to catch them early.
 
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Why shouldn't you fear death?

You shouldn't fear death because it's a natural, inevitable part of life, and accepting it can bring peace, focus your priorities, and encourage living fully in the present, as holding onto life too tightly stems from attachment, while embracing impermanence offers liberation and meaning, with philosophies like Epicurus suggesting fear of death is irrational since "when I am, death is not, and when death is, I am not". 
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What is the top 1 human killer?

Globally and in the U.S., heart disease (cardiovascular disease) consistently remains the number one killer, followed by cancer, with unintentional injuries (accidents) and stroke also high on the list. These conditions account for a large percentage of all deaths, highlighting the significant impact of lifestyle and underlying health factors. 
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What is the rarest plague?

Pneumonic plague is the rarest, but most severe form of the disease. It is 100 percent fatal if not treated rapidly and is deadly in up to half of all cases, even with prompt antibiotic treatment. Untreated cases of bubonic or septicemic plague can become pneumonic plague as infection spreads to the lungs.
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Could you survive the Black Death?

Yes, you could survive the Black Death, especially the bubonic form, but it was extremely risky; survival depended on luck, genetics (like the ERAP2 gene variant for better immune response), isolating from fleas and infected people, and modern antibiotics (which weren't available then) make today's plague highly treatable. In the 14th century, surviving meant avoiding the more deadly pneumonic/septicemic forms and having a strong immune system, with many survivors experiencing better future health and opportunities.
 
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What event killed the most humans?

The event that killed the most humans depends on how "event" is defined, but World War II (70-85 million deaths) and the 1918 Flu Pandemic (50-100 million deaths) are the top contenders for overall single conflicts/pandemics, while the 1556 Shaanxi Earthquake (830,000 deaths) is often cited as the deadliest single natural disaster. Other massive death tolls come from prolonged conflicts like the Mongol Conquests or events like the Black Death, which killed huge portions of populations. 
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How rare is human cannibalism?

Cannibalism, the consumption of another by an individual of the same species, is a widespread practice amongst many animal groups. Human cannibalism or anthropophagy, however, is less common but has been found in many diverse groups ranging from hominids to Crusaders and soldiers in World War II.
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Why did humans start covering their private parts?

Humans started covering private parts for practical reasons like warmth, protection from elements (sun, bugs, thorns), and camouflage, alongside developing social concepts like modesty, status, and cultural norms, with the shift potentially accelerating as societies became more settled and complex, moving from nomadic life to agriculture. While protection came first, social significance grew, eventually leading to cultural ideas that certain body parts are inherently private or shameful. 
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What meat is closest to human skin?

Pigs have very similar skin and flesh

Pig skin is often used as tattoo practice for work on human skin, and those in the know have said that human flesh tastes most similar to pork.
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