Is separation anxiety the last mission in Bo6?

No, "Separation Anxiety" is not the absolute final mission in Call of Duty: Black Ops 6; it's the penultimate mission, with "Checkmate" being the very last, and they are tightly intertwined, often switching between them as you play through the conclusion of the campaign. You complete both "Separation Anxiety" and "Checkmate" to finish the story and see the final cutscene, making them the final major operations.
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Is Separation Anxiety the last BO6 mission?

During the final two missions of the Call of Duty: Black Ops 6 campaign, Separation Anxiety and Checkmate, you will constantly switch from one mission to the other. We've included the links to the interconnected sections of Checkmate below, but you can also see the full Checkmate walkthrough here.
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Is there another ending to the BO6 campaign?

A number of Call of Duty: Black Ops games over the years have had multiple endings, but Black Ops 6 will not continue this tradition. Associate creative director Jon Zuk confirmed this in a new interview. He told IGN, "Black Ops 6 is a linear story, so there is not a branching ending for this one."
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Who is at the end of the Black Ops 6 campaign?

The mysterious man at the end of the Call of Duty: Black Ops 6 campaign, who accesses Daniel Livingstone's computer, is strongly implied to be Jackson Caine, a shadowy Pantheon operative who was also present in the first mission. While his identity isn't explicitly confirmed in-game, Caine's appearance sets up future story elements for the Warzone and seasonal content, continuing the unresolved plot of deep CIA infiltration by the terrorist group. 
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Is Black Ops 7 confirmed?

Call of Duty: Black Ops 7 is a 2025 first-person shooter video game co-developed by Treyarch and Raven Software and published by Activision. It is the twenty-second main installment of the Call of Duty series and is the eighth entry in the Black Ops sub-series, following Call of Duty: Black Ops 6 (2024).
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Call of Duty: Black Ops 6 - Separation Anxiety Mission Walkthrough (No Commentary)

Who is canonically dead in COD?

Both Alex Mason and Jason Hudson are confirmed to be dead from Black Ops 2 canon.
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Why isn't Mason in BO6?

Alex Mason isn't a main character in Call of Duty: Black Ops 6 (BO6) because developers confirmed his canonical death in the Black Ops 2 ending where Woods shoots him in the head (not the leg), making the "leg shot" a non-canon Easter egg, with BO6 focusing on new characters like Adler, Bell, and Caine in the 90s, although his legacy and mentions of his fate exist, with some fans still debating if he could return later in future lore or games. 
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Is it possible to save karma?

Kill DeFalco and rescue Karma (Chloe) during "Karma." In the mission "Karma," you must successfully save Karma by killing DeFalco before he escapes with her. However, if you fail this mission, don't panic yet; you have a second chance to save Karma by doing the strike force mission "Second Chance."
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Is tranzit actually coming back?

Towards the end, he quickly mentioned that Tranzit will be back with Zombies this year...with a small twist. "Tranzit is coming back...in a much scaled up way but this time instead of a bus that drives you around, you're going to be able to do it yourself."
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Which COD has the longest campaign?

While Call of Duty: Black Ops 6 (2024) is highlighted as having one of the longest campaigns with extra content and player choice, traditionally Call of Duty: Black Ops III (BO3) is often cited as having the lengthiest main story for a single-player experience, often taking around 9 hours or more depending on playstyle, with Black Ops 6 aiming to surpass that with added depth and branching paths. Older titles like World at War or CoD 2 also offer substantial length, especially on harder difficulties. 
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Did Black Ops 2 predict 2025?

Yes, Call of Duty: Black Ops II, released in 2012 with much of its action set in 2025, has gained attention for seemingly predicting real-world events, particularly a US-China trade war involving rare earth elements and advanced drone/military tech, sparking discussions about its uncanny foresight in technology, economics, and geopolitical tension as that year arrived. 
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Will there be a 9/11 mission in BO6?

Later, officially, Treyarch said that they are fake and there will be no mission of the 9/11 event.
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What did Adler inject Jane with?

After Russell Adler injected the Phenosorazine drug into Jane Harrow, Troy Marshall interrogated her. Inside her mind - affected by the drug - Harrow tries to reveal what she is planning with the Cradle to Marshall.
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Why is karma alive in BO7?

Karma (Chloe Lynch) is alive in Black Ops 7 by utilizing a specific, less common Black Ops 2 ending where she's captured but not killed, allowing JSOC to rescue her later and leverage her tech skills for the Celerium Worm, fitting into a narrative that bridges disparate BO2 outcomes into a new canon, even if it creates inconsistencies with other paths.
 
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Which karma is hardest?

Deluding karma (Mohanīya karma) – These karmas are an instrumental cause of destruction the soul's right belief and right conduct. Of all karmas, deluding karma is the most difficult to overcome.
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What is killing karma?

Also, it is mentioned in the teachings of the Buddha about the karma of killing. If you kill one sentient being, then for 500 lifetimes you will be killed by others. This is the result of one negative karma of killing.
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Who has the saddest death in COD?

The saddest Call of Duty deaths often involve beloved characters with strong bonds, with frequent mentions including John "Soap" MacTavish, Simon "Ghost" Riley, Roach, Alex Mason, Dimitri Petrenko, Sandman, Elias Walker, and even the presumed death of Viktor Reznov, with fans mourning the loss of camaraderie and the brutal, undeserved nature of these deaths. 
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Should I shoot Harper or Menendez?

In Call of Duty: Black Ops II, to achieve the "best" ending where Menendez is captured and the U.S. avoids war, you must shoot Harper, not Menendez, during the "Achilles' Veil" mission, as this allows your character, Farid, to survive and later save Karma and take a crucial shot for the good ending, even though it's a difficult choice. Shooting Menendez results in Farid's death and prevents the best outcome. 
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What's the saddest death in gaming?

While subjective, the Aerith Gainsborough death in Final Fantasy VII and Lee Everett's sacrifice in The Walking Dead are consistently cited as the saddest, most impactful in gaming history, both for their shocking nature and the deep emotional bonds players formed with them, with Aerith's death shattering norms and Lee's defining a father-daughter bond in an apocalypse. Other contenders include Arthur Morgan (RDR2), Noble Six (Halo: Reach), and Vesemir (The Witcher 3). 
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What happens if you shoot mason in the leg?

If you shoot Alex Mason in the leg (twice) during the "Suffer With Me" mission in Call of Duty: Black Ops II, he survives the encounter, leading to a different outcome in the game's ending where he appears alive, a key part of achieving the "best" or "canon" ending where Woods' life is also saved and Menendez is potentially dealt with differently. Shooting him in the head leads to the common, tragic outcome where Mason dies, altering the ending significantly.
 
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Is harper alive in BO7?

Yes, Mike Harper is alive in Call of Duty: Black Ops 7 (BO7), with his survival stemming from a specific, less common outcome in Black Ops 2 where Farid sacrifices himself to save Karma, leaving Harper alive but injured, a continuity choice that reconciles his presence with the complex BO2 endings.
 
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