What happens if you reroll dad's note?

You generally cannot reroll Dad's Note in The Binding of Isaac; it's a special, unchangeable plot item, and attempts to reroll it (like with The D6 or Spindown Dice) usually do nothing or lead to bugs, though some older versions might softlock, with modern versions often just fading music or leaving an empty pedestal if forced. If obtained outside its intended room, it has no effect, but if you somehow break the game to get it, you can't progress the Ascent.
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What happens if you spindown a sad onion?

Spindown Dice: The Sad Onion disappears upon being rerolled, as its internal ID number is 1. Leaves an empty pedestal.
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Does D4 reroll gulped trinkets?

The items gained by the D4 count towards the collection page. pause screen. remains unchanged. Smelted/Swallowed trinkets (via Marbles, Smelter or Gulp!) will not be rerolled.
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How to get dad's note binding of Isaac?

To get Dad's Note in The Binding of Isaac: Repentance, you must first defeat Mother at least once to unlock the "Strange Door" on Depths II/Necropolis II/Dank Depths II. Then, find the marked skull on that floor, destroy it to get The Fool card (or Telepills), use it to open the Strange Door, and enter the special boss room which contains Dad's Note, leading to the Ascent. 
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Can you reroll a key piece?

Key Piece 2, can be rerolled into any item from the Angel Room pool. This item also counts as a familiar, meaning it takes up a familiar slot.
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What happens if you void or D6 Dad's Note in The binding of Isaac Repentance

Can you open a corpse with mom's knife?

Mom's knife is now able to open the door leading to the Corpse, like it used to in Antibirth. In addition to Mom's Knife, the Forgotten's Bone Scythe and Tainted Eve's Sumptorium are also able to open the door.
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Can I reroll a reroll?

Nope. Any given dice can only be rerolled once.
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Can you reroll dad's note in Isaac?

Dad's note can't be rerolled nor be affected by anything, and on top of that Glitched Crown can't affect plot-items (Polaroid, Broken Shovel parts, Knife Pieces...). That's why nothing happens to it. Dad's Note has no effect if found in any way other than the intended one (in its own special room).
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What's the rarest angel room item?

A: Godhead is often considered one of the rarest and most coveted Angel Room items, especially before all characters and secrets are unlocked.
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Is Jacob or Esau better?

Jacob has less damage and shot speed, while Esau has negative luck, less health and less tears. Even though both have the same base range, Jacob's shot speed reduces his effective range. Apart of that, speed and range are the same as Isaac, so individually there's no much difference from playing Isaac.
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Is rolling a D4 fair?

Are D4 dice fair? Yes, d4 dice are designed to give an equal chance of rolling any of the four possible outcomes. However, it's important to roll them in a way that allows them to tumble and move around. Simply dropping a d4 isn't always a fair way to roll it.
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Can the lost have two holy mantles?

The Lost's Holy Mantle effect is intrinsic to the character once unlocked, and it can't be rerolled. Picking up another one does not double the effect.
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Can D6 reroll into the same item?

Using the D6 on an active item yields different rerolls depending on whether you picked up the active item first. Diplopia will reroll all the items into different items. The copied item will not be rerolled into the same one as the original item.
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What's the difference: shallot vs onion?

So what's the difference between a shallot and an onion? Shallots taste like a cross between red and yellow onions, only less punchy. They have a delicate, sweet flavor with a hint of allium-y sharpness. You can substitute shallots in nearly any recipe that calls for onions—just make sure you're using the same volume.
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Why do we cry if we cut onions?

When an onion is cut, certain (lachrymator) compounds are released causing the nerves around the eyes (lacrimal glands) to become irritated. These compounds consist of methionine and cystine that are part of the amino acid family.
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What is 1001% Isaac?

It unlocks when you have around 276 secrets, that was the total o secrets of Afterbirth, every DLC has its own 100% complete achievement, it's not bugged, you have the number of secrets to unlock the achievement, everything is fine.
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How many hours to 100% TBOi?

Completing The Binding of Isaac (especially with all DLC like Repentance) to 100% can take anywhere from 150 to over 600 hours, with many dedicated players averaging around 300-400 hours, depending heavily on skill, luck, and if you're aiming for "Dead God" (all achievements/completion) or just "Real Platinum God" (main completion). Some estimates for the most challenging achievements suggest potentially thousands of hours, but a focused completionist can finish well within a few hundred. 
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Does the R key reset Angel Room chance?

Upon use, restarts the game to the first floor, keeping all previously collected items. The game timer does not restart. Allows angels rooms to be found even if the previous run included devil deals.
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How to unlock D6 boi?

To unlock the D6 in The Binding of Isaac, you must first unlock and play as the character Blue Baby (???), then defeat the final boss of the Cathedral (Isaac) with them; once unlocked, the D6 becomes Isaac's starting item, allowing him to reroll other items for better options.
 
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How does voiding d infinity work?

Void: When absorbed and Void is used, replicates the effect of a random dice item. Acts as a copy of one of the 10 dice D infinity can replicate. This dice is randomly chosen and does not change.
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What is a gacha reroll?

Rerolling in gacha games is the repetitive process of starting a new account (or resetting a guest account) to redo the initial summons until you get a highly desirable, powerful, or favorite character/item from the game's randomized gacha system. Players do this because new accounts often get generous free currency and pulls, allowing them to aim for the best possible start, saving time and frustration later in the game. 
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Can you reroll uniques?

To reroll a TU, use the unique creation recipe (2AC + oil of enhance). It is much cheaper than wasting an enchanting crystal anyway.
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What is a 2 cost reroll?

In Teamfight Tactics (TFT), the 2-cost reroll strategy is a high-risk, high-reward playstyle that revolves around building a strong team around a specific 2-cost champion.
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