Why is Ellie immune?

Ellie's immunity didn't come because she cordyceps grew with her since birth. She was immune because her system learned to fight it as a newborn and so when she was bitten she was able to fight it off.
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Why was Ellie immune last of us?

Anna also realizes that she was bitten during the fight, before swiftly cutting the umbilical cord connecting her and Ellie. This is the cause of Ellie's Last of Us immunity. Given that the umbilical cord provides babies with oxygen and nutrients, the Cordyceps present in Anna's system is transferred into Ellie.
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Can Ellie infect others?

Ellie Almost Certainly Cannot Infect Others In The Last Of Us. While the end result of what would occur from a group of people eating Ellie - as was threatened in The Last of Us episode 8 - is unclear, there are some hints from The Last of Us Part II surrounding Ellie's immunity and how it works.
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Would Ellie have cured the virus?

However, long-time fans know that the cure was not guaranteed in the game. Ellie still gave the doctors their best hope for creating a cure or vaccine, but it was just as likely that Ellie's death would be for nothing. It's easy to see why HBO chose this route.
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Are there others like Ellie who are immune?

Now 14 years later, Ellie is the only known person to be immune to the Cordyceps infection because -- as Marlene explains via the doctor's examinations -- the infection she was exposed to at birth sent a "chemical message" to the Cordyceps that entered her body when she was bitten.
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Game Theory: Ellie Is NOT Immune! (The Last of Us Part 2)

Is Ellie immune cause her mom was bit?

In the struggle to kill this Infected, Ellie was born. However, Anna was bitten. Anna quickly cut Ellie's umbilical cord, but not before the Infected reached Ellie. Since the cordyceps has grown in Ellie since birth, the cordyceps believe that Ellie herself is cordyceps, resulting in immunity.
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Is Ellie the only immune The Last of Us?

Ellie was literally irreplaceable. As far as anyone knew she was the only person on the world who was immune. And their plan was to immediately kill her.
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Is Joel immune last of us?

Ellie is the only known case of Cordyceps immunity, having been infected with a mutated benign strain. Joel has avoided infection, but it's safe to say that he's a “mere mortal”.
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Do they ever find a cure The Last of Us?

No, because the surgeon who would have removed Ellie's brain is permanently stopped in his tracks by Joel. But it certainly sounds viable enough. The problem is, if the Firefly doctor is right, Ellie's brain could literally hold the cure for cordyceps. But while she's still alive, humankind won't be able to access it.
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Could Ellie have been used to make a cure?

From a scientific perspective, it's not clear that Ellie's immunity could have led to a cure or vaccine. In the real world, we still don't have any vaccines for fungus infections.
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Does Ellie's blood cure Sam?

Before going to sleep, he reveals that to Ellie, and the girl tries to lift his spirits by spreading a little of her own blood over his wound. She's immune to the cordyceps, so maybe it has some effect. But it didn't have. When Ellie wakes up, Sam is already dead and turned.
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Does Ellie's mom get Infected?

Eventually, the infected finds her and the two have a scrap on the floor in which Anna is bitten, but she also gives birth to Ellie in the process. Anna cuts the umbilical cord, but this occurs after she was bitten and starts to succumb to the infection herself.
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Why can Ellie breathe spores?

The infection caused Ellie as a fetus to be exposed to the cordyceps and this is the cause of her immunity.
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Did Ellie's mom cut the umbilical cord?

She finally makes it inside, but the infected runner isn't far behind, and she's bitten just before she gives birth to Ellie. Realizing she has seconds, she quickly cuts the umbilical cord – despite her later protestations to Marlene that she was bitten after she did this.
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How did Joel find out Ellie was immune?

However, we don't know that for sure until Joel (Pedro Pascal) and Ellie make it to the Fireflies in Salt Lake City. After Joel and Ellie are attacked, Joel wakes up in a hospital room with Marlene (Merle Dandridge), who explains to him what their doctor's tests on Ellie's immunity have uncovered.
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Who is Ellie's dad?

In the end, Ellie's lack of a real dad has less to do with Jesus and more to do with Joel. Ellie's lack of a father figure in her life makes Joel the perfect figure for her to latch onto, just as Joel's loss of a teenage daughter makes Ellie one of the few people in the world who can force her way into his heart.
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Why did the fireflies stop looking for a cure?

I also discovered that many many years after the initial outbreak they were still looking for a cure until the 15 year mark hit on the infection when the Fireflies and the organizations around the world stopped looking for a cure/vaccine because the technology they needed was no longer accessible.
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Does Joel find a cure?

Joel kills the doctors before they try to synthesize a cure from Ellie's blood, meaning that nobody knows if a cure was actually possible in the HBO show. However, Ellie's immunity to the Infected is never used to make a cure in any of The Last of Us games, with this possibility never being resolved.
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Does Ellie find out Joel lied?

"She knows he's not telling the truth," Ramsey says. "But she can't let herself believe it because it's too painful and it's too scary, the idea that her only purpose in life hasn't been fulfilled — that that had been taken away from her by the person that she loves and trusts the most.
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How was Joel not Infected?

It turns out Joel may have narrowly avoided being infected simply because of his food choices on the series' pilot. Early on season one, episode three, Ellie asks Joel how the infection began. "If you have to get bit to be infected than who bit the first person?" Ellie asks.
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Why was Joel killed?

In the video game's sequel, “The Last of Us Part II,” Joel is shockingly murdered in the first act of the game by Abby, the daughter of the Firefly surgeon Joel killed in order to let Ellie live. Joel's death sets Ellie up on a mission of revenge against Abby.
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Is the Cordyceps virus real?

Yes.

The fungus from The Last of Us is based on a real fungus that exists in nature today and is called Ophiocordyceps unilateralis, or cordyceps. Cordyceps is often referred to as the “zombie-ant fungus” because it primarily infects ants and other insects such as spiders.
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How did Ellie survive the bite?

The finale implies Ellie's immunity is linked to Anna's bite on her inner thigh, corroborating a fan theory that Ellie's built-in protection against the cordyceps outbreak was the result of her mother somehow getting bitten before childbirth.
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Why did Ellie stab the infected?

Speaking with Vanity Fair, Ramsey explains Ellie's decision to cut the infected before killing it. According to Ramsey, Ellie is thinking of people close to her in that scene. To Ellie, it is as if this infected person killed Riley and Tess, even if it wasn't the same infected.
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What happened to Ellie's mom?

After the outbreak, she became pregnant and gave birth to her daughter, who she named Ellie, sometime in 2019. She died within a day of giving birth to her, but she had the time to write Ellie a letter. Before Anna died, Marlene promised to look after Ellie in her absence.
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