Will Piper hate you if you side with the Institute?

Yes, siding with the Institute will disappoint and upset Piper significantly because she despises them and their synth-replacement practices, but she generally won't leave you or become hostile unless you commit extreme acts against innocents; she'll express strong disapproval, making it a challenging companion dynamic for an Institute playthrough.
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What does Piper do if you side with the Institute?

If one finishes Nuclear Family and sides with the Institute, when later talking to Piper, she might be distraught and angry at them for putting the Institute in power, though will still remain a companion option.
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What companions do you lose if you side with the Institute?

If you join the Institute you lose Danse and Deacon. Each companion has their own likes and dislikes for certain activities, including decisions made regarding the faction you choose to finish the game with.
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How does Piper feel about the Institute?

Piper hates the Institute and is elated if you blow it up. She fears and loaths it. BUT she likes Synths and thinks they are people, intelligent and self-aware. She loves the Railroad, she loves Nick, she likes Curie and hates you being bigoted against robots. Meanwhile Synth Nat did nothing wrong.
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What happens if I side with the Institute in Fallout 4?

Joining the Institute in Fallout 4 makes you part of a secretive, technologically advanced faction that builds synths (androids) and seeks to control the Commonwealth's future, granting you access to powerful tech, instant travel via teleporter, clean supplies, and a unique storyline where you eventually become its leader, but it also turns the Brotherhood of Steel and Railroad into permanent enemies, forcing a conflict with them by the game's end.
 
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Fallout 4 Piper's reaction to siding with the Institute

What's the best faction to side with in Fallout 4?

There's no single "best" faction in Fallout 4; it depends on your playstyle and morals, but generally, the Railroad (for stealth/espionage rewards like Ballistic Weave) and Brotherhood of Steel (BoS) (for Power Armor/heavy weapons) offer great perks, while the Minutemen (for a true "good guy" feel and settlement focus) are morally sound but less rewarding, and the Institute is often seen as the villainous, technologically advanced, but morally corrupt choice.
 
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Who is the real villain in Fallout 4?

The main villain in Fallout 4 is Shaun, also known as Father, the leader of the high-tech Institute and the adult son of the player character, the Sole Survivor, who seeks to replace humanity with synths and uses his parent as a pawn in his plan to take over the Commonwealth. Other antagonists include Conrad Kellogg, the mercenary who kidnaps Shaun, and the entire Institute, as well as other factions like the Minutemen, Brotherhood of Steel, and Railroad having morally grey or villainous elements depending on player choice. 
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Who is the weakest companion in Fallout 4?

Strong is definitely the worst companion. That said my number one go to for backup and great dialog is R4-04. after her i would say as far as usefulness goes, Piper, Cait, Curie, Ada ''Assaultron legs'' crazy fast''. X6-88 , Valentine, Hancock, Danse, Deacon.
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Can you romance two companions in Fallout 4?

Yes, you can romance multiple companions in Fallout 4, even all of them, as relationships aren't mutually exclusive; however, you need to manage who is present during flirt/romance interactions to avoid negative affinity, though they generally don't fight, and you only get the "Lover's Embrace" XP buff from one person at a time. 
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Which faction does Piper like?

In Fallout 4, Piper (Piper Wright) generally favors the Minutemen and the Railroad, aligning with their focus on helping common people and synths, but dislikes the authoritarianism and secrecy of the Brotherhood of Steel and the Institute's cruelty, though you can manage affinity by being diplomatic. She approves of helping civilians, lockpicking, and peaceful solutions, while disapproving of excessive violence, looting settlements, and siding too heavily with the Brotherhood or Institute.
 
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Is it better to return or deliver the Deathclaw egg in Fallout 4?

Putting the helmet on after completing the quest by returning the egg will immediately turn the deathclaw hostile. Berry Mentats will also trigger a hostile status. If one delivers the egg for the reduced reward having stolen it back from the nest a pristine deathclaw egg may remain in the player's inventory.
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Can I join all three factions in Fallout 4?

You can join all factions up until the quest mass fusion. Once you start that, you have to pick a side. There is also a quest the bos will give you to kill all the leaders of rr, this will make you enemies with rr before you start mass fusion. If you dislike rr, this may be an enjoyable quest for you.
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How to tell if a settler is a synth?

There is a 50/50 chance that the accused is actually a synth, but the only ways for the Sole Survivor to know for sure are to interrogate them (a hard dialogue check), see if they have increased Energy Resistance (Awareness required), or kill them and check their corpse for a synth component.
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Is it better to take Nick or Piper to the memory den?

You can take either Nick Valentine or Piper Wright to the Memory Den for the "Dangerous Minds" quest in Fallout 4; Nick is crucial to the main storyline and has unique dialogue, while Piper also offers good reactions and potential affinity gain, but Nick will always meet you there regardless, making the choice more about personal preference or early game utility, as both offer benefits for the Memory Den sequence. 
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Why does Piper call you blue?

Piper calls the player "Blue" in Fallout 4 because of the iconic blue Vault Jumpsuit that Vault Dwellers wear, signifying their origin from Vault 111; even if you change outfits, she uses it as a nickname for your "fish out of water" status and Pip-Boy, recognizing you as someone from a Vault.
 
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Is CX404 dogmeat from Fallout 4?

Yes, CX404 from the Fallout TV show is the series' version of the iconic companion Dogmeat, a nod to the beloved German Shepherd in Fallout 4 and other games, but CX404 is a distinct Belgian Malinois with her own Enclave origin story, connecting the show's narrative to the games.
 
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Can you befriend a deathclaw in Fallout 4?

Yes, you can tame Deathclaws in Fallout 4, primarily through the Wasteland Workshop DLC to capture them in cages for your settlements or, uniquely, through the Devil's Due quest to get a permanent, named companion by returning its egg. The DLC method involves building cages and using Beta Wave Emitters to pacify them for settlement defense or arena battles, while the quest offers a free-roaming friend. 
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Is there NSFW content in Fallout 4?

Sex & Nudity

This is completely optional choice of dialogue by the player. Self-induced, completely skippable. Some raiders have barely revealed clothes. Nothing explicit or innapropriate.
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Who is the best ally in Fallout 4?

Once you maximize your bond, unique affinity perks unlock, and you may find them incredibly useful during your upcoming adventures.
  • Fallout 4: All Companions Ranked – Best Allies for the Wasteland.
  • Dogmeat.
  • Curie.
  • Paladin Danse.
  • Porter Gage (Nuka-World DLC)
  • Strong.
  • Preston Garvey.
  • Nick Valentine.
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Is Piper a good follower?

Yes, Piper is widely considered a great Fallout 4 companion, especially early on, for her valuable "Gift of Gab" perk (double XP for discoveries/charisma checks) and fun personality, though she's a weak fighter and can break stealth; players often give her better weapons like a Wastelander's Friend.
 
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Who nuked Shady Sands in Fallout?

In the Fallout TV series, Hank MacLean, a Vault-Tec executive and Overseer of Vault 33, ordered the nuclear destruction of Shady Sands in 2283 to eliminate the flourishing New California Republic (NCR) and prevent the surface world's true history from being revealed to the Vaults. He used his access and Vault-Tec connections, possibly involving the Enclave or pre-war technology, to deploy a nuclear weapon, erasing the NCR's capital and its burgeoning society. 
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Is Preston Garvey suicidal?

Deep down, although not actively suicidal, Preston says he simply had given up hope for himself and the Minutemen and did not care if he lived or died; if he was going to meet his end, he would do it fighting as the last true believer in the Minutemen's justice.
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What does Codsworth call Nate?

If you call your self “Nate” (the actual name of the male sole survivor) Codsworth will sometimes refer you as “Mr. Nate”.
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