Does dad's key work on hush?

No, Dad's Key cannot open the entrance to Hush (The Blue Womb) after the 30-minute time limit has passed in The Binding of Isaac, but it can open doors from the inside after the fight, and other items like Mama Mega or Strange Key work on the timed doors. Dad's Key opens most locked doors, including Boss Rush and Hush doors before their timers expire, but fails if you're too late.
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Does dad's key open hush?

No, Dad's Key cannot open the door to the Blue Womb (Hush's floor) from the outside if you've passed the 30-minute timer, but it can open other locked doors like Mega Satan's or secret rooms, and it can open the Hush door from the inside to exit the room after the fight. The key is that Dad's Key won't work for time-sensitive boss doors (Hush/Boss Rush) once their time limit is up, though it will open regular rooms on that floor. 
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What doors does dad's key open?

Upon activation, all closed doors in the current room Isaac is in will be opened; this includes Challenge Rooms, rooms in The Chest and even rooms where there are bosses and enemies (except for the fight with Mom).
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Can dad's key get you out of boss rush?

No, Dad's Key cannot open the Boss Rush door from the outside if the 20-minute timer has already expired, but it can let you escape the Boss Rush from the inside after you've entered. It's a common misconception that it opens all locked doors, but the timer-locked Boss Rush and Hush doors are key exceptions, though Dad's Key still saves time by opening other locked rooms quickly. 
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Which two keys cannot open a door?

This is a riddle, and the common answer points to non-physical keys like a monkey wrench (a tool) and a piano key (part of an instrument) that, while called "keys," don't open physical doors, or sometimes even the playful "donkey" and "monkey" (as in "donkey's key" or "monkey's key") because they are animals, not locks. 
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Official TBOI Item Guides No. 175: Dad's Key

Does Dad's Key open the mausoleum?

Dad's key works on the downpour door, mines door, and mausoleum door for sure.
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What happens if you reroll dad's note?

Dad's note can't be rerolled nor be affected by anything, and on top of that Glitched Crown can't affect plot-items (Polaroid, Broken Shovel parts, Knife Pieces...). That's why nothing happens to it. Dad's Note has no effect if found in any way other than the intended one (in its own special room).
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Why is Mom's knife so good?

Effects. Isaac's tears are replaced by a knife that pierces enemies and can travel through obstacles. Holding down the fire button increases its range and power. The knife deals damage 20 times per second upon contact with enemies while Isaac is holding it.
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What is the hardest challenge in TBOi?

The Binding Of Isaac Rebirth: 10 Hardest Challenges, Ranked
  1. 1 Ultra Hard. Ultra Hard, as the name would lead you to believe, is the hardest challenge in The Binding of Isaac: Rebirth.
  2. 2 SPEED! ...
  3. 3 Aprils Fool. ...
  4. 4 Purist. ...
  5. 5 Family Man. ...
  6. 6 Cat Got Your Tongue. ...
  7. 7 BRAINS! ...
  8. 8 Suicide King. ...
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What do you unlock after beating mom's heart 11 times?

Unlock Method

After being killed 11 times, Mom's Heart is permanently replaced by It Lives. However, even after being replaced by It Lives, there are a few circumstances in which Mom's Heart can still be fought: It can still appear in the Nightmare Boss wave of Chapter 4 in Greed/Greedier Mode.
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Is Hush difficult with Isaac?

overall, Hush can be difficult, but with practise fighting him becomes more bearable over time.
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Can you go to Hush after R key?

Using R Key now resets the timer completely, allowing for another go at Boss Rush or Hush.
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Does the eraser work on hush?

Eraser on Hush's first form prevents his second from spawning.
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How to unlock beast tboi?

To unlock The Beast in The Binding of Isaac: Repentance, you must first beat Mother on the alternate path to reveal a Strange Door on Depths II/Necropolis II, then use the Polaroid or Negative after the standard Mom fight to enter, pick up Dad's Note to start the Ascent, and finally beat Dogma in Home, leading to The Beast fight.
 
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How to unlock a strange door in TBOi?

To unlock the Strange Door in The Binding of Isaac: Repentance, you first need to beat Mother on the alternate path to unlock it, then find it in the starting room of Depths/Necropolis II and give it The Polaroid or The Negative to enter the path to Home, requiring a teleport out of Mom's room after beating Mom. 
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What has keys but can't?

So who got this Riddle correct?; What has many keys but can't open a door? Ans: Piano or a Keyboard.
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How to solve the two door riddle?

To solve the two-door riddle (one guard lies, one tells the truth), ask either guard: "Which door would the other guard say leads to freedom (or treasure)?" Both will point to the wrong door, so you then choose the opposite door to find safety. 
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Can you unlock a door if there is a key in the other side?

Yes, you can often unlock a door if a key is in the other side, depending on the lock type, especially with emergency function or friction cylinders that allow double-sided key entry, but for standard locks, you might need a locksmith, specialized tools like bump keys, or clever tricks like using shims or pushing the key out if the lock allows. 
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What does Mom's bra do in Isaac?

In The Binding of Isaac, Mom's Bra is an active item that petrifies (freezes) all enemies in the current room for about 4-5 seconds, letting you attack them freely, though you still take contact damage from frozen enemies. It has a 3-room charge and adds to the "Yes Mother?" item set, contributing to a transformation when three items from that set are collected. 
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Why does Paget Brewster wear a wig?

Paget Brewster as Emily Prentiss on Criminal Minds: Evolution. "On the original series, I wore a wig for the last year," she shared. "I thought our show was over and we weren't going to continue. I wanted to see what work was out there and I wanted to look different from Prentiss.
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What happens after beating mom's heart 5 times?

If I recall correctly, after beating Mom's Heart 5 times it changes to It Lives!, which is a variation on the Heart fight. Beating that 5 times unlocks Sheol and Cathedral as options for next floor, beating each of those 5 times opens up the floor beyond that respectively.
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